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| Study challenges routine use of MRI scans to evaluate breast cancer Sat, 06 Sep 2008 00:00:00 EDT |
(Fox Chase Cancer Center) A new study suggests women with newly-diagnosed breast cancer who receive an MRI after their diagnosis face delays in starting treatment and are more likely to receive a mastectomy. The study, presented today at the 2008 ASCO Breast Cancer Symposium, also shows that despite lack of evidence of their benefit, the routine use of MRI scans in women newly diagnosed increased significantly between 2004 and 2005, and again in 2006. |
| Creating lung cancer risk models for specific populations refines prediction Fri, 05 Sep 2008 00:00:00 EDT |
(University of Texas M. D. Anderson Cancer Center) Lung cancer risk prediction models are enhanced by taking into account risk factors by race and by measuring DNA repair capacity, according to research teams led by epidemiologists at the University of Texas M. D. Anderson Cancer Center in two complementary papers appearing in the September issue of Cancer Prevention Research. |
| UNC spin-off company receives $2 million grant to market cancer treatment technology Fri, 05 Sep 2008 00:00:00 EDT |
(University of North Carolina at Chapel Hill) A University of North Carolina at Chapel Hill spin-off company has been awarded a $2 million grant to commercialize a new technology to improve radiation treatment of prostate cancer. |
| Computerized reminder system drove up colon cancer screening rates, U-M study found Fri, 05 Sep 2008 00:00:00 EDT |
(University of Michigan Health System) A computerized reminder system used in community-based primary care doctors' offices increased colorectal cancer screening rates by an average of 9 percent, according to a new study from the University of Michigan Health System. |
| Atomic structure of the mammalian 'fatty acid factory' determined Fri, 05 Sep 2008 00:00:00 EDT |
(ETH Zurich/Swiss Federal Institute of Technology) Mammalian fatty acid synthase is one of the most complex molecular synthetic machines in human cells. It is also a promising target for the development of anti-cancer and anti-obesity drugs and the treatment of metabolic disorders. Now researchers at ETH Zurich have determined the atomic structure of a mammalian fatty acid synthase. Their results have just been published in Science magazine. |
| African-Americans have unique lung cancer risks from chronic obstructive pulmonary disease Fri, 05 Sep 2008 00:00:00 EDT |
(American Association for Cancer Research) Scientists at the M.D. Anderson Cancer Center have developed a risk prediction assessment for lung cancer specifically for African-Americans that suggests a greater risk from chronic obstructive pulmonary disease, according to a report published in the September issue of Cancer Prevention Research, a journal of the American Association for Cancer Research. |
| JCI online early table of contents: Sept. 5, 2008 Fri, 05 Sep 2008 00:00:00 EDT |
(Journal of Clinical Investigation) This release contains summaries, links to PDFs and contact information for the following newsworthy papers to be published online, September 5, 2008, in the JCI: "How STDs increase the risk of becoming infected with HIV"; "HIV-stimulated immune cells generate cells with immunosuppressive properties"; "How immune cells help tumors grow blood vessels"; "Type 2 diabetes under stress"; and "Stuck on you: FGF proteins help ensure cells lining blood vessels stick together." |
| 1 step back ... 2 steps forward Fri, 05 Sep 2008 00:00:00 EDT |
(Georgetown University Medical Center) Women with hormone-receptor positive, metastatic breast cancer may take medications for years to help keep their cancer at bay, but when the tumor becomes resistant to anti-hormonal drugs, treatment with chemotherapy becomes the only option. But a study presented today may change this approach. Early data suggests a new treatment approach can "re-sensitize" the tumor, allowing anti-hormonal drugs to do their job once again. |
| Collaboration between researchers yields more comprehensive portrait of brain cancer Thu, 04 Sep 2008 00:00:00 EDT |
(HudsonAlpha Institute for Biotechnology) A team including researchers at the HudsonAlpha Institute and Stanford University, together with colleagues from a number of other organizations, today publishes a comprehensive analysis of genomic variation in the brain cancer glioblastoma. These results are the first from the Cancer Genome Atlas research network, a collaborative effort funded by the National Cancer Institute and the National Human Genome Research Institute of the National Institutes of Health. |
| 31st Annual San Antonio Breast Cancer Symposium Thu, 04 Sep 2008 00:00:00 EDT |
(American Association for Cancer Research) The CTRC-AACR San Antonio Breast Cancer Symposium features the latest cutting-edge findings in laboratory, translational and clinical breast cancer research. This year's meeting focuses on new and promising therapeutic approaches, as well as strides being made in diagnosing and preventing breast cancer. |
| Gaining a better understanding of kidney diseases Thu, 04 Sep 2008 00:00:00 EDT |
(Helmholtz Association of German Research Centres) By introducing a genetic switch in mice it is possible to increase or decrease the production of specific protein molecules in their kidneys. Thus, researchers can study the influence of specific proteins on disease development. Scientists of the German Cancer Research Center, Heidelberg University Hospitals and other research institutes have published this model of investigating severe kidney diseases in the latest issue of Nature Medicine. |
| Potential remedy for the 'mental fog' in cancer patients Thu, 04 Sep 2008 00:00:00 EDT |
(Springer) Cancer patients have complained for years about the mental fog known as chemobrain. Now in animal studies at West Virginia University, researchers have discovered that injections of N-acetyl cysteine, an antioxidant, can prevent the memory loss that breast cancer chemotherapy drugs sometimes induce. The WVU researchers' study has just been published in the September issue of the Springer journal Metabolic Brain Disease. |
| Massive cancer gene search finds potential new targets in brain tumors Thu, 04 Sep 2008 00:00:00 EDT |
(Dana-Farber Cancer Institute) An array of broken, missing and overactive genes have been identified in a genetic survey of glioblastoma, the most common and deadly form of adult brain cancer, report scientists from Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard. The large-scale combing of the brain cancer genome confirms the key roles of some previously known mutated genes and implicates a variety of other genetic changes that may be targets for future therapies. |
| Unsuccessful drug against anxiety opens a novel gateway for the treatment of cancer Thu, 04 Sep 2008 00:00:00 EDT |
(University of Helsinki) An unsatisfying drug for anxiety reveals to scientists a promising novel anti-cancer drug target, state researchers from the University of Helsinki, Finland. |
| International team reveals first prognosticator of survival in aggressive cancer Thu, 04 Sep 2008 00:00:00 EDT |
(Sbarro Health Research Organization) The tumor suppressor gene pRb2/p130 may provide the first independent prognostic biomarker in cases of soft tissue sarcoma, according to an international collaboration of researchers, including scientists at the Sbarro Institute for Cancer Research and Molecular Medicine at the College of Science and Technology at Temple University in Philadelphia, PA, the department of human pathology and oncology, University of Siena and the Center of Oncological Research of Mercogliano in Avellino, Italy. |
| Discovery challenges fundamental tenet of cancer biology Thu, 04 Sep 2008 00:00:00 EDT |
(Yale University) Yale researchers have identified an unusual molecular process in normal tissues that causes RNA molecules produced from separate genes to be clipped and stitched together. The discovery that these rearranged products exist in normal as well as cancerous cells potentially complicates the diagnosis of some cancers and raises the possibility that anti-cancer drugs like Gleevec could have predictable side effects. |
| Studies spot numerous undiscovered gene alterations in pancreatic and brain cancers Thu, 04 Sep 2008 00:00:00 EDT |
(Howard Hughes Medical Institute) HHMI investigators have detected a multitude of broken, missing, and overactive genes in pancreatic and brain tumors, in the most detailed genetic survey yet of any human tumor. Some of these genetic changes were previously unknown and could provide new leads for improved diagnosis and therapy for these devastating cancers. |
| The Cancer Genome Atlas reports first results of comprehensive study of brain tumors Thu, 04 Sep 2008 00:00:00 EDT |
(NIH/National Human Genome Research Institute) The Cancer Genome Atlas Research Network, a collaborative effort funded by the National Cancer Institute and the National Human Genome Research Institute of the National Institutes of Health, today reported the first results of its large-scale, comprehensive study of the most common form of brain cancer, glioblastoma. |
| Comprehensive genetic blueprints revealed for lethal pancreatic, brain cancers Thu, 04 Sep 2008 00:00:00 EDT |
(Johns Hopkins Medical Institutions) The complete genetic blueprint for lethal pancreatic cancer and brain cancer was deciphered by a team at the Johns Hopkins Kimmel Cancer Center. |
| M. D. Anderson study finds racial disparities in radiation therapy rates for breast cancer Wed, 03 Sep 2008 00:00:00 EDT |
(University of Texas M. D. Anderson Cancer Center) Black women are less likely than white women to receive radiation therapy after a lumpectomy, the standard of care for early stage breast cancer, according to a new study by researchers at the University of Texas M. D. Anderson Cancer Center. |
| M. D. Anderson study finds change in HER2 status after treatment with Herceptin Wed, 03 Sep 2008 00:00:00 EDT |
(University of Texas M. D. Anderson Cancer Center) Researchers at the University of Texas M. D. Anderson Cancer Center have discovered that when treated with Herceptin prior to surgery, 50 percent of HER2 positive, breast cancer patients showed no signs of disease at the time of surgery. However, of those women who had residual disease, about one-third had tumors that converted from HER2 positive to HER 2 negative status -- possibly indicating a resistance to the targeted therapy. |
| ASTRO honors Boston brain cancer survivor with Survivor Circle Award Wed, 03 Sep 2008 00:00:00 EDT |
(American Society for Therapeutic Radiology and Oncology) The American Society for Therapeutic Radiology and Oncology has selected Debra DeMella as the recipient of the 2008 Survivor Circle Award. Ms. DeMella will receive her award and a $1,000 check to be given to the charity of her choice Monday, Sept. 22, 2008, at 1 p.m. during ASTRO's 50th Annual Meeting, which will take place Sept. 21-25, 2008, at the Boston Convention and Exhibition Center. |
| NYU Cancer Institute researcher among first NIH EUREKA award recipients Wed, 03 Sep 2008 00:00:00 EDT |
(NYU Langone Medical Center / New York University School of Medicine) Michelle Krogsgaard, Ph.D., assistant professor of pathology at the NYU Cancer Institute, is the first NYU School of Medicine recipient of the EUREKA award. |
| Scientists produce nanoscale droplets with cancer-fighting implications Wed, 03 Sep 2008 00:00:00 EDT |
(University of California - Los Angeles) UCLA scientists have succeeded in making unique nanoscale droplets that are much smaller than a human cell and can potentially be used to deliver pharmaceuticals. |
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