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Laparoscopic surgery for bladder cancer leads to good long-term cancer control
(Wiley) Long-term survival rates following laparoscopic surgery for bladder cancer are comparable to those of open surgery, according to a study published in BJU International.

High-dose flu vaccine superior for frail elderly living in long-term care facilities
(University of Pittsburgh Schools of the Health Sciences) The high-dose flu vaccine is significantly better than the regular flu shot at boosting the immune response to the flu virus in frail, older residents of long-term care facilities, according to the results of a University of Pittsburgh School of Medicine study. It is the first evaluation of the vaccine in long-term care residents, which is the population most vulnerable to flu-related death.

High-dose flu vaccine appears better for frail older adults in long-term care
(Infectious Diseases Society of America) For frail older adults living in long-term care facilities, the high-dose influenza vaccine appears to be a better option than the regular shot, producing a stronger immune response than the standard vaccine, according to a study published in The Journal of Infectious Diseases and now available online. High-dose vaccine may play a key role, along with improving vaccination rates among health care workers and other strategies, in preventing flu in this vulnerable and growing population.

Fine particulate air pollution linked with increased autism risk
(Harvard School of Public Health) Women exposed to high levels of fine particulate matter specifically during pregnancy -- particularly during the third trimester -- may face up to twice the risk of having a child with autism than mothers living in areas with low particulate matter, according to a study from Harvard School of Public Health. The greater the exposure, the greater the risk, researchers found. It was the first US-wide study exploring the link between airborne particulate matter and autism.

Researcher to cancer: 'Resistance will be futile'
(University of Montreal) Turning the tables, Katherine Borden at the University of Montreal's Institute for Research in Immunology and Cancer has evoked Star Trek's Borg in her fight against the disease.

A survey of the general population in France identifies knowledge gaps in the perception of lung cancer
(International Association for the Study of Lung Cancer) A prospective nationwide survey on perceptions of lung cancer in the general population of France highlights a need for increased public education on the benefits of lung cancer screening, the good survival rates of early-stage disease and the improved outcomes with new therapeutic strategies, including targeted-therapies.

Targeted next-generation sequencing reveals a high number of genomic mutations in advanced malignant
(International Association for the Study of Lung Cancer) Next generation sequencing in malignant pleural mesothelioma tumors shows a complex mutational setting with a high number of genetic alterations in genes involved in DNA repair, cell survival and cell proliferation pathways. Increased accumulation of mutations correlates with early progression of the tumor and decreased survival.

Weigh-in once a week or you'll gain weight
(Cornell Food & Brand Lab) Stepping on the scale is common among dieters but how does the frequency of weigh-ins impact weight? A new study in PLOS ONE showed that the more frequently dieters weighed themselves the more weight they lost, and if participants went more than a week without weighing themselves, they gained weight.

Health coaching paired with gym membership works best for obese people with mental illness
(The Geisel School of Medicine at Dartmouth) A health promotion program, called In SHAPE, designed for people with serious mental illness, produced more fit participants and significant weight loss than a control group where participants only received a gym membership. The results of a randomized clinical trial, published in the Dec. 12 American Journal of Psychiatry, Dr. Stephen Bartels of Dartmouth and colleagues showed that more than half the participants in the In SHAPE group achieved clinically significant reduction in cardiovascular risk.

Genetic mutation found to cause ovarian failure
(American Friends of Tel Aviv University) A new Tel Aviv University study throws a spotlight on a previously-unidentified genetic cause of Primary Ovarian Insufficiency, associated with infertility in 1 percent of all women worldwide. While the genes involved in chromosome duplication and division had been shown to cause POI in animal models, this is the first time a similar mutation has been identified in humans.

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