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Testing for EGFR mutations and ALK rearrangements is cost-effective in NSCLC.
(International Association for the Study of Lung Cancer) Multiplexed genetic screening for epidermal growth factor receptor and anaplastic lymphoma kinase gene rearrangements and subsequent biomarker-guided treatment is cost-effective compared with standard chemotherapy treatment without any molecular testing in the metastatic non-small cell lung cancer setting in the United States.

Complex environments push 'brain' evolution
(University of Wisconsin-Madison) Little animations trying to master a computer game are teaching neuroscience researchers how the brain evolves when faced with difficult tasks. Neuroscientists at the University of Wisconsin-Madison and Michigan State University have programmed animated critters that they call 'animats.' The critters have a rudimentary neural system made of eight nodes: two sensors, two motors, and four internal computers that coordinate sensation, movement and memory.

Obamacare Co-ops show promise and peril
(Brown University) The health insurance co-ops spawned under Obamacare have had an impact in the marketplace, but their long-term viability will depend on their mettle in the marketplace, writes Eli Y. Adashi, former dean of medicine and biological sciences, and medical student Allan Joseph in a JAMA viewpoint article.

Erectile dysfunction drugs could protect liver from sepsis-induced damage, says Pitt team
(University of Pittsburgh Schools of the Health Sciences) Drugs that are on the market to treat erectile dysfunction could have another use: they might be able to protect the liver from damage caused by sepsis, a systemic inflammatory response to infection, say researchers at the University of Pittsburgh School of Medicine. They recently published their findings in Science Signaling.

Study finds texting may be more suitable than apps in treatment of mental illness
(Clemson University) Texting may be a more suitable treatment aid for those with mental illness than mobile applications.This is the key finding of a new study led by researchers from Clemson University in collaboration with researchers from Indiana University and the Centerstone Research Institute. The study was published in the journal Personal and Ubiquitous Computing.

Probiotic helps treat diabetes in rats, could lead to human remedy
(Cornell University) Science may be one step closer to treating diabetes with a human probiotic pill, according to new Cornell University research. The researchers engineered a strain of lactobacillus, a human probiotic common in the gut, to secrete a Glucagon-like peptide 1. They then administered it orally to diabetic rats for 90 days and found the rats receiving the engineered probiotic had up to 30 percent lower high blood glucose, a hallmark of diabetes.

UC San Diego, UC San Francisco launch new cancer cell mapping initiative
(University of California - San Diego) Researchers from the University of California, San Diego School of Medicine and University of California, San Francisco, with support from a diverse team of collaborators, have launched an ambitious new project -- dubbed the Cancer Cell Map Initiative or CCMI -- to determine how all of the components of a cancer cell interact.

'Feeding and fasting' hormone adropin can improve insulin action
(Saint Louis University) New research from a Saint Louis University scientist holds promise for type 2 diabetes treatment.

First-ever view of protein structure may lead to better anxiety drugs
(Michigan State University) When new medicines are invented, the drug may hit the intended target and nullify the symptoms, but nailing a bull's eye -- one that produces zero side effects -- can be quite elusive.New research conducted at Michigan State University and published in the current issue of Science has, for the first time, revealed the crystal structure of a key protein, TSPO, which is associated with several forms of anxiety disorders.

Walking on ice takes more than brains
(Salk Institute) Salk scientists discover how a 'mini-brain' in the spinal cord aids in balance.

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