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New compounds protect nervous system from the structural damage of MS
(The Mount Sinai Hospital / Mount Sinai School of Medicine) A newly characterized group of pharmacological compounds block both the inflammation and nerve cell damage seen in mouse models of multiple sclerosis, according to a study conducted at the Icahn School of Medicine at Mount Sinai and published online this week in the journal Nature Neuroscience.

Researchers detail reasons for ibrutinib therapy discontinuation in CLL
(Ohio State University Wexner Medical Center) About 10 percent of patients with chronic lymphocytic leukemia discontinued therapy with the Bruton tyrosine kinase inhibitor drug ibrutinib because of disease progression during clinical trials, according to a study published online in JAMA Oncology by scientists at The Ohio State University Comprehensive Cancer Center Arthur G. James Cancer Hospital and Richard J. Solove Research Institute.

Enhancing studies on a possible blood biomarker for traumatic brain injury
(NYU Langone Medical Center / New York University School of Medicine) New technology being introduced at NYU Langone Medical Center could help researchers advance blood biomarker capabilities that show changes in low concentrations of specific proteins present following a neurological injury.

Crohn's disease not exempt from racial disparities
(Nationwide Children's Hospital) A study found significant differences in hospital re-admissions, medication usage, and both medical and surgical complications of children with Crohn's disease related to race. In the study, black children had a 1.5 times higher frequency of hospital re-admissions because of Crohn's disease compared to white children.

Hospitals participating in ACS NSQIP significantly improve surgical outcomes over time
(American College of Surgeons) The majority of hospitals participating in the American College of Surgeons National Surgical Quality Improvement Project improve surgical outcomes over time, and improvement continues with each year that hospitals participate in the program, according to a new study published online today in Annals of Surgery.

For patients with brain tumors, insurance status linked to differences in patient safety and quality of care
(Wolters Kluwer Health) Patients that are on Medicaid or uninsured have higher rates of reportable patient safety and quality of care issues during hospitalization for brain tumors, reports a study in the March issue of Neurosurgery, official journal of the Congress of Neurological Surgeons. The journal is published by Wolters Kluwer.

Reviving drugs with anti-stroke potential, minus side effects
(Emory Health Sciences) Emory scientists have found NMDA receptor antagonists that can limit damage to the brain in animal models of stroke, apparently without the pronounced side effects seen with similar drugs.

Mount Sinai researchers find chemotherapy after bladder cancer surgery improved survival
(The Mount Sinai Hospital / Mount Sinai School of Medicine) Patients that received chemotherapy after bladder cancer surgery demonstrated an approximately 30 percent lower risk of death than those that underwent surgery alone.

Study examines physician-industry conflict of interest issue from MS patient perspective
(University of Vermont) A new study explores what multiple sclerosis patients know, and want to know, about their physician's financial relationship with the pharmaceutical company sponsoring a clinical trial.

Mystery of the reverse-wired eyeball solved
(American Physical Society) Counter-intuitively, in vertebrates photoreceptors are located behind the neurons in the back of the eye. Now physicists explain why the neural wiring seems to be backwards.

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